Natera is at the forefront of personalized genetic testing, transforming the management of disease worldwide. As we scale our life-saving diagnostics, we are transforming our approach to software quality and reliability.

We are seeking a seasoned and visionary Director of Engineering, Product Integration to lead a newly formed Product Integration team. You will pivot our strategy from traditional, late-stage configuration testing to a proactive, end-to-end integration function that de-risks our most complex "Pillar" projects (eg, LCGP, Signatera IVD). This role requires a leader who is AI-native, hands-on, and high agency. You will act as the "Integration Quarterback" for the engineering organization, defining the "Golden Paths" through our distributed architecture and driving an incremental, milestone-based validation strategy. You will live the ethos of agile, user-centered development, using modern tools to create leverage and ensure our software works seamlessly from order to report.

• Strategic Leadership & Vision: Transform Integration Strategy by transitioning from the Legacy PSPC model to a modern, risk-based approach. Define a vision where testing is a continuous, value-added activity Embedded in the development lifecycle.
• High Agency Execution: Champion urgency and ownership. Proactively identify integration risks during design (shifting left) rather than waiting for code freeze.
• AI-Native Leverage: Pioneer the use of AI and LLMs to revolutionize testing. Implement strategies to auto-generate test cases from PRDs, use AI for intelligent log analysis and root cause detection, and dramatically increase throughput.

• The "Quarterback" Model: Serve as the integration lead for major company initiatives. Partner with Solution Architects to define "Integration Milestones" and extract iterative builds from component teams to validate workflows progressively.
• End-to-End Ownership: Own validation of critical business workflows across the full stack (Portal -> LIMS -> Lab Execution -> Bioinformatics -> Reporting). Ensure that the "Happy Path" is unbreakable and unhappy path support is in place.
• User-Centered Validation: Go beyond spec compliance to verify the user experience. Ensure the integrated system delivers value to clinicians and patients, using realistic production-like data.
• Environment Strategy: Act as gatekeeper for Staging/Integration environments. Enforce strict configuration management and version control to reflect Production reality.

• Build a High-Performance Team: Recruit and mentor a new breed of integration leads who understand microservices architecture and business logic.
• Foster Innovation: Create an environment where the team experiments with new tools (eg, chaos engineering, AI agents) to break the system before users do.

• 10+ years of engineering experience, with at least 5 years in leadership roles managing complex software integration, QA, or SDET teams.
• Deep Technical Expertise: Strong background in testing distributed systems, microservices, and event-driven architectures (Kafka, AWS). Understand that integration means API contracts, data consistency, and system resilience.
• Transformation Experience: Proven track record of turning around underperforming testing functions or building "Zero-to-One" quality organizations in rapid-growth environments.
• Regulated Industry Experience: Familiarity with healthcare standards (HIPAA, CLIA, FDA) is strongly preferred, but a demonstrated ability to bring rigor to complex regulated environments is essential.
• BS/MS in Computer Science, Engineering, or related field.

• User-Centered: You obsess over the end-user experience. You understand that a passing API test is meaningless if the clinician cannot view the report.
• High Agency: You don't wait for permission to fix broken processes. You navigate ambiguity with confidence and drive cross-functional alignment.
• Technical Fluency: Ability to work deeply with architects on API schema design and with product managers on user journey mapping.

This range reflects a good-faith estimate of the base pay we reasonably expect to offer at the time of hire. Final compensation will vary based on experience, qualifications, and internal equity considerations. This position is eligible for additional compensation and benefits through Natera's Total Rewards program, including:

• Annual performance incentive bonus
• Long-term equity awards
• Comprehensive health benefits (medical, dental, vision)
• 401(k) with company match
• Generous paid time off and company holidays
• Additional wellness and work-life benefits

Compensation Range
$171,400-$214,300 USD

Natera is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women's health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.

The Natera team includes statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and more from world-class institutions, who care deeply for our work and each other. When you join Natera, you'll work hard and grow quickly, alongside industry leaders, and be part of a company changing the landscape of genetic disease management.

Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and more. We also offer a generous employee referral program.

For more information, visit the company website. Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. All qualified applicants will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws.

If you are based in California, we encourage you to read this important information for California residents. Link: https://www.natera.com/notice-of-data-collection-california-residents/

Please be advised that Natera will reach out to candidates with a @natera.com email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes.

For More Information
BBB announcement on job scams, FBI Cyber Crime resource page